Immune System Dysfunction in the Elderly.
نویسندگان
چکیده
Human aging is characterized by both physical and physiological frailty that profoundly affects the immune system. In this context aging is associated with declines in adaptive and innate immunity established as immunosenescence. Immunosenescence is a new concept that reflects the age-associated restructuring changes of innate and adaptive immune functions. Thus elderly individuals usually present chronic low-level inflammation, higher infection rates and chronic diseases. A study of alterations in the immune system during aging could provide a potentially useful biomarker for the evaluation of immune senescence treatment. The immune system is the result of the interplay between innate and adaptive immunity, yet the impact of aging on this function is unclear. In this article the function of the immune system during aging is explored.
منابع مشابه
External human exposure and management immune system in pathogenesis of irritable bowel syndrome
External exposed radiation may play an important role in pathogens of irritable bowel syndrome (IBS), although is thought to arise due to a combination of genetic and environmental factors. The result is dysregulated immune responses due to alteration in the gut microbiota population and the subsequent development of gut inflammation. It has recently been shown that the effect of ioni...
متن کاملCOVID-19: The potential role of nutritional deficiencies, global climatic changes, and immune system dysfunction
متن کامل
The Effect of Pilates Training on Immune Markers in Elderly Men
Introduction: With age, the immune system decreases. Improving immune function in the elderly through exercise has an important role in the health of the elderly. The purpose of the present study was to determine the effect of twelve weeks of Pilates training on immune markers in elderly men. Methods: In this quasi-experimental study, 22 elderly men with mean age (65 ± 2.81) years were purpose...
متن کاملComments on Common Intestinal Parasites in Elderly People
Intestinal parasites (IP) are one of the most significant causes of infections among the eldely in developing countries, especially in tropical areas. Trichuris trichiura and Ancylostoma duodenale infect near 2.3 billion people, especially in elderly in all around the world (1). Intestinal protozoan like Giardia lamblia, Entamoeba histolytica and Cryptosporidium parvum are widespread in o...
متن کاملEffects of exercise training on improving the immune system of elderly people at the time of COVID-19 pandemic: A systematic review
متن کامل
The Effect of Resistance Training with Theraband on the Transforming Growth Factor-β in the Elderly Women
Background: Ageing and physical inactivity can negatively affect immune system. On the contrary, a healthy lifestyle and physical activity can improve immune system and prevent from mild inflammatory diseases. Transforming Growth Factor-β (TGF-β) can play an important role in the regulation of immune function and inflammation. This study aimed to investigate the effects of 8 weeks of theraband ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Anais da Academia Brasileira de Ciencias
دوره 89 1 شماره
صفحات -
تاریخ انتشار 2017